VASCULAR

In 1998, the Nobel Prize¹ in Physiology or Medicine was awarded to three American scientists for the discovery of nitric oxide (NO) as a signaling molecule (miracle molecule) in the cardiovascular system.

This nitric oxide is produced in the endothelium, this is the inner layer of our veins. To produce this nitric oxide the endothelium needs L-Arginine.

Important vascular properties of nitric oxide are:^{1 , 2}

Ability to slightly dilate blood vessels.
Ability to relax blood vessels.
Maintenance of optimal blood vessel tension and structure,
Rejuvenation of the vascular system.
Lowering of blood pressure.
Improvement of chemical processes in the cells.

Nitric Oxide and your cardiovascular system.

Nitric Oxide¹ is naturally made in our bodies.

A Nobel Prize was awarded for the discovery that Nitric Oxide plays a significant role in the cardiovascular system.

This discovery revealed Nitric Oxide(NO) as a vasodilator, helping to reduce blood pressure and increase oxygen in the blood. Produced by the lining of the blood vessels know as the endothelium, Nitric Oxide acts as a messenger molecule telling blood vessels to widen or dilate and contract or relax, like an elastic band.

With enough Nitric Oxide, blood vessels can relax and widen allowing blood to flow from and to the heart.

As we age we produce less Nitric Oxide.This can cause the cardiovascular system to become less elastic which can reduce the flow of oxygenated blood to vital organs.

This is the reason it’s important to have an active lifestyle and a diet that’s rich in nitrates, which converts to Nitric Oxide and may help maintain normal blood pressure levels and a healthy cardiovascular system.

The combination of amino acids in Recover-Me in the correct ratio and palatinose (disaccharide), a slow-burning, non-cariogenic carbohydrate, has a strong supporting role in the slow release of nitric oxide conversion.⁴

Back Ground

Until we reach adulthood, the body produces enough nitric oxide to keep the endothelium cells relaxed and flexible. That is why most young people don’t have hypertension or other forms of circulatory problems.

As the years passes most of us develop a hardening of the vascular system, making it less flexible and unable to adjust to circumstantial blood pressure changes. This makes it more difficult for the heart to pump blood and can cause serious trauma.

This is one reason why heart attacks and strokes are the number one killer in the western world.

Improve the blood flow to the heart.

If you want to improve your heart health you need to improve the flexibility of your vascular system.

This improvement will also benefit all other functions in our organs, bones, brain and skin tissue.

Improving Blood Flow to the Kidneys.

The kidneys play an important role in regulating blood pressure. It’s a densely vasodilated organ whose main purpose is to filter waste products and excess salts and water from the bloodstream.

When blood passes through the glomerulus (microscopic filters) removing bacteria, dead cells and waste products (at a rate of about 570 ml per minute) and balances minerals, salts and water before re-entering the bloodstream via the renal vein.

Without this balancing process, nerves, muscles, and other tissues in your body will not work optimally. Kidneys also play an important role in regulating hormone function.

Improving Blood Flow to the Liver.

The liver is an organ that is clearly affected by nitric oxide.^5,6

Your liver is an important organ. You cannot live without it. For example, your liver has the following important functions: bile formation. carbohydrate metabolism, protein metabolism, fat metabolism, detoxification, cleansing and storage.

In order to perform all these different functions, there are two separate systems present in your liver:

The circulatory system: The liver contains a lot of blood. The blood from the intestines enters through the portal vein. This allows important nutrients from the intestines to be transported to the liver. The liver cells can then convert, store or release these nutrients back into the blood vessels when your body needs them.
The bile duct system: The liver produces bile. Through many bile ducts in the liver, this bile is transported to the gallbladder where it is stored.

Dr. L.J. Ignarro explains.³

Dr Ignarro winner of the Nobel Prize in Medicine (1998), has dedicated more than 30 years of research in the discovery of Nitric Oxidebenefits and preventing and even reversing cardiovascular disease.The benefits don’t stop there. It can also reduce high blood pressure, lower cholesterol and age-proof your cardiovascular system. IIn the adjacent video, Dr. L.J. Ignarro explains what nitric oxide is and the important role of L-Arginine in the production of nitric oxide. We have transcribed the text below.

Dr. L.J. Ignarro : Cardio-artery disease occurs when there is an impairment of blood flow to the heart. The heart has its own circulatory system and that circulatory system is called the coronary arteries. When people develop arteriosclerosis or high cholesterol-levels this can result in plaque deposition and plaque formation in the arteries.

And as those plaques grow and grow they can obstruct the flow of blood. This can lead to a decrease in the flow of blood and therefore the flow of nutrients and oxygen to the heart to a point that when you need your heart when doing exercise or walking up the stairs, if the heart is not getting enough blood or oxygen it is going to feel pain due to ischemicdamage, that is in essentially a heart attack.

Nitric Oxide is a chemical, or a molecule or you can even call it a hormone that is present in the body, which functions in certain specific ways within the cardiovascular system.

It is our way, of protecting ourselves literally against cardio vascular disease.

For example, it is a molecule, that lowers blood pressure. It is our body's mechanism to prevent strokes and heart attacks.The arteries produce nitrogen oxideswith the aim of lowering blood pressure, improving blood flow to the organs, because Nitric Oxide is a vasodilator,it widens or relaxes, the arteries so that more blood can flow through them.

This lowers the pressure within the arterial system (blood vessels) and protects us from coronary artery disease because it can lower bad cholesterol levels and more.

video about cholesterol.

Nitric oxide production in the arteries is the natural way to protect against heart disease provided we make enough of it.

Nitric Oxide is considered to be a life saver because it is the body’s natural way of protecting against cardiovascular disease.

Cardiovascular disease is the number one cause of death around the world and the body can protectitself against all of these heart disease by producing more and more nitric oxide.

When Nitric Oxide becomes deficient it is when the barriers break down, this is when the protection is lost and the individual is very sensitive and very receptible to heart disease.

And again Nitric oxide is protective because it can keep your blood pressure down in the normal range high blood pressure causes heart attacks, causes strokes and can lead to arteriosclerosis or coronary artery disease and Nitric Oxide can prevent all of these things." Thus Dr. L.J. Ignarro.

In the video to the left, Dr. L.J. Ignarro further explains the numerous benefits of nitric oxide. We have transcribed the text for you below.

Nitric oxide ensures that all organs in the body receive the normal amount of blood and therefore nutrients and oxygen that is required.In addition, nitric oxide can interfere with the blood clotting processand so, it can prevent unwanted blood clotting.

When people suffer from a heart attack in many cases this is due to a blood clot that develops in the coronary arteries that feed blood to the heart. By the same mechanism when a person gets a stroke. This is generally due to the development of a blood clotin the cerebral arteries that carry blood to the brain.

So nitric oxide is something we make to prevent that unwanted clotting of blood.It iss a vasodilator, which means it is going to widen those blood vessels and lower the pressure within the blood vessels. And it doesn't lower blood pressure if the blood pressure is normal.

That is the beauty about the natural substances present in our body. The nitric oxide senses when the blood pressure is abnormally elevated and then it steps in to reduce that blood pressure, back down to the normal range not below normal.

Nitric oxide is something that you cannot simply take from the outsideyou can not take it in a pill you can't put it in a water or anything like that, because nitric oxide is actually a gaseous substance and it is very unstable, it doesn't last for more than a second or two so you can't really take nitric oxide.

What you can do though is you can take the ingredients that the body uses to make nitric oxide and that will stabilise the nitric oxide prevent it from breaking down and lasting longer in your body." Thus dr. L.J. Ignarro.

The endothelium, the inner artery wall, needs L-Arginine^{see video above} to produce nitric oxide. Administration of L-Arginine alone is not sufficient to allow all the benefits of the amino acid to play a significant role in the body. After long bone growth has stopped (around the age of 23), the body's ability to absorb L-Arginine becomes increasingly limited. ⁷

RECOVER-ME IS A UNIQUE FORMULA OF AMINO ACIDS THAT INCREASES THE PRODUCTION OF NITRIC OXIDE IN THE BLOOD VESSELS.⁴

Interesting facts........

The vascular system is complex and consists of kilometres of veins and arteries that all work with the heart to pump blood to and from your cells.
In 1998, the Nobel Prize in Physiology or Medicine was awarded to three American scientists for the discovery of nitric oxide as a signal molecule in the cardiovascular system.
The nitric oxide derived from L-Arginine is directly or indirectly involved in virtually every cellular function and health condition imaginable, from the cardiovascular system to the immune system and from hormone function to nerve function. Also called the "miracle molecule".

L-Arginine is the direct precursor of NO, (nitric oxide) urea, ornithine and agmatine and is necessary for the synthesis of creatine.
One of the most important properties of L-Arginine is its ability to induce vasodilation and relax blood vessels.
There is abundant evidence that the endothelium plays a critical role in the maintenance of vascular tone and structure.
An important endothelium-derived vasoactive mediator is nitric oxide (NO), an endogenous messenger molecule. NO is formed in healthy vascular endothelium and L-Arginine is an important source.

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